{"iri":"https://folio.openlegalstandard.org/R6e0IIeTTMVoQl5cw3E3co","label":"Mantle Cell Lymphoma","sub_class_of":["https://folio.openlegalstandard.org/RBFOZ6k0p0FnZyMzuijRYdU"],"parent_class_of":[],"is_defined_by":null,"see_also":[],"comment":null,"deprecated":false,"preferred_label":null,"alternative_labels":["Aggressive B-Cell Lymphoma","Cyclin D1 Positive Lymphoma","Mantle Zone Lymphoma"],"translations":{},"hidden_label":null,"definition":"Mantle cell lymphoma is an aggressive type of non-Hodgkin lymphoma that originates in the B-cells located in the mantle zone of the lymph nodes. It is characterized by a specific genetic mutation involving the overexpression of the cyclin D1 protein, leading to uncontrolled cell growth.","examples":[],"notes":[],"history_note":null,"editorial_note":null,"in_scheme":null,"identifier":null,"description":null,"source":null,"country":null}