# Mantle Cell Lymphoma

**IRI:** https://folio.openlegalstandard.org/R6e0IIeTTMVoQl5cw3E3co

## Labels

**Alternative Labels:**

- Aggressive B-Cell Lymphoma
- Cyclin D1 Positive Lymphoma
- Mantle Zone Lymphoma

## Definition

Mantle cell lymphoma is an aggressive type of non-Hodgkin lymphoma that originates in the B-cells located in the mantle zone of the lymph nodes. It is characterized by a specific genetic mutation involving the overexpression of the cyclin D1 protein, leading to uncontrolled cell growth.

## Sub Class Of

- https://folio.openlegalstandard.org/RBFOZ6k0p0FnZyMzuijRYdU

**Deprecated:** False