<owl:Class xmlns="https://folio.openlegalstandard.org/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:v1="http://www.loc.gov/mads/rdf/v1#" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" xmlns:folio="https://folio.openlegalstandard.org/" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" rdf:about="https://folio.openlegalstandard.org/R6e0IIeTTMVoQl5cw3E3co">
  <rdfs:subClassOf rdf:resource="https://folio.openlegalstandard.org/RBFOZ6k0p0FnZyMzuijRYdU"/>
  <rdfs:label>Mantle Cell Lymphoma</rdfs:label>
  <skos:altLabel>Aggressive B-Cell Lymphoma</skos:altLabel>
  <skos:altLabel>Cyclin D1 Positive Lymphoma</skos:altLabel>
  <skos:altLabel>Mantle Zone Lymphoma</skos:altLabel>
  <skos:definition>Mantle cell lymphoma is an aggressive type of non-Hodgkin lymphoma that originates in the B-cells located in the mantle zone of the lymph nodes. It is characterized by a specific genetic mutation involving the overexpression of the cyclin D1 protein, leading to uncontrolled cell growth.</skos:definition>
</owl:Class>