{"iri":"https://folio.openlegalstandard.org/RCeiGFdK6TTSZb0MaH3Uj3P","label":"Tay-Sachs Disease","sub_class_of":["https://folio.openlegalstandard.org/R8LxIR1bsgFd3td2G24G3mq","https://folio.openlegalstandard.org/REFNhmFYG6yk3W0RPLFV6g"],"parent_class_of":[],"is_defined_by":null,"see_also":[],"comment":null,"deprecated":false,"preferred_label":null,"alternative_labels":["GM2 Gangliosidosis Type I","Hexosaminidase A Deficiency"],"translations":{},"hidden_label":null,"definition":"Tay-Sachs disease is a rare, inherited neurodegenerative disorder caused by a deficiency of the enzyme hexosaminidase A. This deficiency leads to the accumulation of GM2 gangliosides, which are toxic to nerve cells.","examples":[],"notes":[],"history_note":null,"editorial_note":null,"in_scheme":null,"identifier":null,"description":null,"source":null,"country":null}