# Tay-Sachs Disease

**IRI:** https://folio.openlegalstandard.org/RCeiGFdK6TTSZb0MaH3Uj3P

## Labels

**Alternative Labels:**

- GM2 Gangliosidosis Type I
- Hexosaminidase A Deficiency

## Definition

Tay-Sachs disease is a rare, inherited neurodegenerative disorder caused by a deficiency of the enzyme hexosaminidase A. This deficiency leads to the accumulation of GM2 gangliosides, which are toxic to nerve cells.

## Sub Class Of

- https://folio.openlegalstandard.org/R8LxIR1bsgFd3td2G24G3mq
- https://folio.openlegalstandard.org/REFNhmFYG6yk3W0RPLFV6g

**Deprecated:** False